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These are typically human-built head-altering chemical compounds that happen to be both sprayed on dried, shredded plant material so read more they may be smoked or marketed as liquids to become vaporized and inhaled in cigarettes and various products.

The rationale for read more your transform towards the quinolone substructure is unknown, but it might are actually discovered being an acceptable replacement for that naphthoyl moiety that is at this time regulated by US scheduling legal guidelines.[eighty two]

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PB-22 and 5F-PB-22 were being the 1st synthetic cannabinoids to include a quinoline substructure and an ester linkage. These compounds are believed to happen to be synthesized Together with the intention of making a synthetic cannabinoid prodrug, which could make improvements to absorption and confound detection. Ester bonds are simply biodegradable by way of spontaneous or endogenous, nonspecific esterase hydrolysis, which has been commonly Employed in medicinal chemistry to make ester prodrugs.

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